After Effects On the Spot[c] Time-Saving Tips and Shortcuts from the Pros

In Living Colorama IV: Spot Color

If you want to change the color of an object in a scene, such as someone's shirt, do so with Colorama.

Twirl open the Pixel Selection parameter group and change Matching Mode to RGB. Use the Eyedropper next to Matching Color to click on the shirt. Only the shirt colors will be modified by the Output Cycle color wheel.