Manual of Rheumatology and Outpatient Orthopedic Disorders (LB Spiral Manuals)

Appendix D. Normal Laboratory Values

Manual of Rheumatology and Outpatient Orthopedic Disorders


Appendix D. Normal Laboratory Values

Stephen A. Paget and Allan Gibofsky

Immunologic

Hematologic

Biochemistry

Endocrine

Quantitative urinary excretion

Table D-1. Normal laboratory values

Tests Normal values

Immunologic  
Rheumatoid factor  
       Latex fixation <1.160 titer
       Rate nephelometric <30 IU/mL
Serum complement  
       Total hemolytic complement (CH 50) 150 “250 Us/mL
       Complement components (immunoassays)  
           C1q    11 “22 mg/dL
           C2    1.6 “3.6 mg/dL
           C3    64 “210 md/dL
           C4 11.5 “50.0 mg/dL
           C5    7.1 “20.4 mg/dL
           C1 esterase inhibitor    14 “30 mg/dL
           Factor B 14.8 “31.0 mg/dL
Antinuclear antibody (ANA) Negative
Anti-DNA antibody ( Crithidia immunofluorescence) Negative
Anti-streptolysin O (ASO) 0 “125 Todd units
Serum immunoglobulins (immunoassay)  
       IgG 723 “1685 mg/dL
       IgA    69 “382 mg/dL
       IgM    63 “277 mg/dL

Hematologic    
Blood counts Males Females
       CBC (includes five-part differential) 3.5 “10.7    3.5 “10.7
       RBC — 10 12 /L 4.2 “5.6    4.0 “5.2
       HGB (g/dL) 13 “17 11.5 “16.0
       HCT (%) 38 “52    34 “46
       MCV (fl) 82 “98    82 “98
       PLT — 10 9 /L 160 to 400  
Differential % Absolute
       Neutrophils 40.0 “74.0 1.90 “8.00
       Lymphocytes 19.0 “48.0 0.90 “5.20
       Monocytes 3.4 “9.0 0.16 “1.00
       Eosinophils 0.0 “7.0 0.00 “0.80
       Basophils 0.0 “1.5 0.00 “0.20
       Larger unstained cells 0.0 “4.0  
Stained smears ”bands   0 “12 mm/h males <10%
Sedimentation rate (Westergren)   0 “27 mm/h females
Activated partial thromboplastin time (aPTT)   Upper limit 38.0 sec
Prothrombin time (PT) (dependent on reagent lot No.)   Upper limit 13.0 sec
Fibrinogen   200 “400 mg/dL

Biochemistry  
Acid phosphatase (spectrophotometry)      0 “5.5 µ/L
Albumin (modified Doumas)  3.5 “5.0 g/dL
Aldolase (ultraviolet, kinetic)      0 “7.4 µ/L
Alkaline phosphatase (Bowers & McComb)  30 “110 µ/L
Amylase (enzymatic /kinetic)  25 “125 µ/L
Bicarbonate (enzymatic oxidation)  23 “35 mEq/L
Bilirubin, total (azobilirubin)      0 “1.0 mg/dL
Calcium ( o -cresophthalein complex 1)  8.5 “10.5 mg/dL
Chloride (ion-selective electrode)  97 “107 mEq/L
Cholesterol (enzymatic) 150 “240 mg/dL
Creatine kinase (enzymatic/kinetic)  40 “175 females

 40 “225 µ/L males

Creatinine (modified Jaffe)  0.4 “1.2 mg/dL
GGTP (modified Rosalki & Tarlow)      0 “70 µ/L
Glucose (hexokinase)    70 “105 mg/dL
Iron (ferrozine)  20 “170 µg/dL

 females

 20 “200 µg/dL

 males

Iron-binding capacity (ferrozine) 250 “450 µg/dL
LDH (modified Amador)  80 “200 µ/L
5'-NT ( enzyme kinetic)    4 “11.5 µ/L
Phosphorus, inorganic (modified Fiske & Subbarow)  2.5 “5.0 mg/dL
Potassium (ion-selective electrode)  3.5 “5.0 mEq/L
Protein, total (Biuret)  6.0 “8.0 g/dL
Salicylate (colorimetric You & Roe) therapeutic level    6 “20 mg/dL
SGOT (AST) (modified Scandinavian)  10 “45 µ/L
SGPT (ALT) (modified Scandinavian)      0 “40 µ/L
Sodium (ion-selective electrode) 135 “145 mEq/L
Triglyceride (enzymatic/colorimetric)  72 “174 mg/dL
Urea nitrogen (modified Talke & Schubert)    5 “25 mg/dL
Uric acid (uricase Trivedi)  2.0 “9.0 mg/dL

Endocrine  
T 4 (immunoassay)  4.9 “10.7 µg/dL
T 3 uptake (immunoassay)    28% “36%
T 3 RIA (immunoassay)  
       0 to 14 y 125 “250 ng/dL
       14 to 23 y 100 “220 ng/dL
       > 24y  80 “180 ng/dL
Intact PTH (immunochemiluminescent assay)  1.0 “5.0 pmol/L
N-terminal PTH (immunochemiluminescent assay)      0 “6.1 pmol/L
C-terminal PTH (radioimmunoassay)      0 “50 mEq/mL

Quantitative urinary excretion  
Calcium  50 “400 mg/24 h
Hydroxyproline, total  15 “45 mg/24 h
Magnesium  75 “150 mg/24 h
Sodium  43 “217 mg/24 h
Potassium  26 “123 mEq/24 h
Phosphorus (inorganic) 340 “1,100 mg/24 h
Amylase (enzymatic/kinetic)    1 “17 U/h
Protein  10 “100 mg/24 h
Creatinine 800 “1,900 mg/24 h
Creatinine clearance  70 “180 mL/min
Uric acid (diet-dependent) 250 “750 mg/24 h

Books@Ovid

Copyright 2000 by Lippincott Williams & Wilkins

Stephen A. Paget, M.D., Allan Gibofsky, M.D., J.D. and John F. Beary, III, M.D.

Manual of Rheumatology and Outpatient Orthopedic Disorders

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